Open Dialogue versus Treatment as Usual for Adults in Mental Health Crisis: Insights from the ODDESSI Multisite Cluster-Randomised Trial in England

MedXY Editorial Team•Sep 2, 2026•Clinical Updates

Open Dialogue, a network-oriented, person-centred mental health care model, was assessed in a large multisite cluster-randomised trial across England.
The primary endpoint, time to first relapse post-recovery, showed no significant difference between Open Dialogue and treatment as usual over two years.
Open Dialogue demonstrated significant reductions in psychiatric inpatient admission rates and re-referral to crisis or specialist services.
Service users receiving Open Dialogue reported enhanced recovery experiences, better quality of life, and greater satisfaction with care without safety concerns.

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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.