Evaluating the Safety of Standardized Tranexamic Acid Dosage in Facelift Surgery: Insights from a Large Retrospective Cohort

Highlight

• Standardized tranexamic acid (TXA) dosing mixed with local anesthetic was evaluated in over 1,000 facelift patients under intravenous sedation.
• No increase in ischemic, vascular, or systemic complications was identified with TXA use compared to controls.
• TXA showed a comparable rate of distal flap vascular compromise, managed effectively without permanent sequelae.
• The study supports TXA’s safety in rhytidectomy with controlled dosing protocols.

Study Background