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Bone Health Index: A Novel Fracture Risk Assessment in Pediatric Osteogenesis Imperfecta

MedXY Editorial Team•Sep 1, 2026•Diabetes & Endocrinology
pediatric DXAfracture riskOsteogenesis ImperfectaBHIBone Health Indexchildren

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The Bone Health Index (BHI) quantifies average cortical thickness of metacarpal bones to assess fracture risk in children with Osteogenesis Imperfecta (OI). BHI demonstrated superior predictive performance for fractures over conventional DXA-based bone mineral density (BMD) measurements, especially in infants under five. This method provides a practical, radiation-efficient alternative where DXA is unavailable or technically challenging.

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