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A 2026 Mendelian randomization study supports high BMI as a causal risk factor for vascular-related dementia, with part of the effect mediated through elevated systolic and diastolic blood pressure.
Experts have released the VasCog-2-WSO criteria, an updated international standard for diagnosing vascular cognitive impairment and dementia. This revision introduces a preclinical stage and incorporates modern neuroimaging and fluid biomar
A pooled analysis of three large cohorts found no consistent association between circulating lipoprotein(a) and Alzheimer’s disease or vascular dementia, but genetic evidence for very small apo(a) isoforms suggests a modest increase in Alzh
Metabolic syndrome—characterized by five key metabolic risk factors—significantly increases the risk of dementia, especially vascular dementia, among older adults. Early detection and lifestyle interventions are crucial to protect brain hea