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MedXY AI/MedXY News/Tag: TYK2-JAK1 inhibitor
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TYK2-JAK1 inhibitor

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Skin-Specific Outcomes of Brepocitinib in Dermatomyositis: Evidence from a Phase 3 Randomized Clinical Trial and Secondary Analysis
Clinical UpdatesbrepocitinibDermatomyositis

Skin-Specific Outcomes of Brepocitinib in Dermatomyositis: Evidence from a Phase 3 Randomized Clinical Trial and Secondary Analysis

By MedXY|Sep 3, 2026

Brepocitinib, a selective TYK2-JAK1 inhibitor, showed rapid, sustained skin disease control, itch relief, and improved quality of life in dermatomyositis patients over 52 weeks with an acceptable safety profile in a global phase 3 trial.

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