Psychiatryschizophreniadopamine
Pluralistic Model Proposed for Schizophrenia Spectrum: Beyond Dopamine
By MedXY|Jul 24, 2026
A new narrative review synthesizing evidence from 1980 to 2025 argues that schizophrenia spectrum disorders cannot be explained solely by dopaminergic dysfunction. The authors propose a pluralistic model involving multiple neurochemical and cellular processes, with implications for treatment development and biomarker-based stratification.
