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Emergency Medicine

Emergent Interfacility Transfers for Ischemic Stroke in the U.S.: Patterns and Implications from 2016 to 2022

This study analyzes national trends in emergent interfacility ischemic stroke transfers among Medicare beneficiaries, revealing shifts in transfer rates, patient characteristics, and hospital features associated with transferred versus nont

Sep 19, 2026
Neurology

High-Resolution Disconnectome Enhances Prognostic Accuracy and Guides Thrombectomy Decisions in Basilar Artery Occlusion

This study demonstrates that quantifying disconnected white matter fibers via high-resolution disconnectome analysis predicts 90-day outcomes and identifies thrombectomy responders better than conventional measures in acute basilar artery o

Sep 14, 2026Sign in to read
Neurology

Baseline Ischemic Burden Influences Tenecteplase Benefit Before Thrombectomy in Acute Stroke: Insights from the BRIDGE-TNK Trial

A post hoc analysis of the BRIDGE-TNK trial reveals that intravenous tenecteplase before endovascular thrombectomy significantly improves functional independence in acute large-vessel occlusion stroke patients with extensive baseline ischem

Aug 22, 2026
Neurology

Sex Differences in Large Vessel Occlusion Screening and Thrombectomy Outcomes: Insights from a Population-Based Cohort Study in Ontario

This study reveals that female stroke patients are less frequently screened for large vessel occlusion (LVO) yet have a higher LVO prevalence and comparable thrombectomy use to males, with better long-term outcomes post-thrombectomy.

Jul 13, 2026
Emergency Medicine

Earlier IV Thrombolysis Before Thrombectomy Was Linked to Better In-Hospital Stroke Outcomes in RES-Q

A large multinational RES-Q registry analysis suggests that the benefit of bridging thrombolysis before thrombectomy is greatest when treatment starts very early, with attenuation after 150 minutes.

May 7, 2026Sign in to read
Neurology

Pediatric Ischemic Stroke in Switzerland Is Still Diagnosed Too Late for Reperfusion in Most Cases

A 24-year Swiss registry study shows modest improvement in pediatric stroke recognition, but most children are still diagnosed beyond thrombolysis and thrombectomy windows.

May 3, 2026
Cardiology

Timing Extubation After Thrombectomy: Evidence from the EDESTROKE Trial and Advanced Post-Reperfusion Management

The EDESTROKE trial finds no significant difference in 90-day functional outcomes between early (<6h) and delayed (6-12h) extubation post-thrombectomy, shifting focus toward microvascular and hemodynamic optimization.

Apr 5, 2026
Neurology

Beyond Recanalization: Understanding the Dynamic Evolution of the No-Reflow Phenomenon After Stroke Thrombectomy

A prospective multicenter study reveals that the no-reflow phenomenon is a dynamic, evolving pathology following successful thrombectomy. It is significantly associated with infarct growth and poor functional outcomes, suggesting that achie

Mar 10, 2026
Neurology

Time-Dependent Topography: How Specific ASPECTS Regions Predict Outcomes in Early vs. Extended Window Large Vessel Occlusion Stroke

A post-hoc analysis of 1,040 LVO stroke patients reveals that the prognostic value of specific brain regions varies significantly between early (0-6h) and extended (6-24h) time windows, identifying the insula, caudate, and M6 as early-windo

Feb 4, 2026
Neurology

Long-Term Gains vs. Short-Term Risks: Decoding the Role of Bailout Angioplasty in Acute Large Vessel Occlusion

The ANGEL-REBOOT trial reveals that while bailout angioplasty (BAOS) increases short-term procedural risks, it significantly improves one-year functional outcomes and reduces stroke recurrence in patients with failed thrombectomy or high-gr

Jan 18, 2026
Neurology

Emergent Carotid Stenting During Thrombectomy Superior for Tandem Lesion Stroke: Insights From the CERES-TANDEM Study

The CERES-TANDEM study provides Class II evidence that emergent carotid stenting (eCAS) during endovascular thrombectomy for tandem lesions significantly improves 90-day functional outcomes without increasing hemorrhagic risk, supporting it

Jan 6, 2026
Neurology

Emergent Carotid Stenting Redefines Outcomes in Tandem Lesion Stroke: Insights from the CERES-TANDEM Study

The multicenter CERES-TANDEM study provides Class II evidence that emergent carotid stenting (eCAS) during thrombectomy for tandem lesions significantly improves 90-day functional recovery without increasing the risk of symptomatic intracra

Jan 6, 2026Sign in to read
Cardiology

The PERT Revolution: Rising Catheter-Directed Therapy Adoption Correlates with Improved Pulmonary Embolism Outcomes

A multicenter registry study reveals that Pulmonary Embolism Response Teams (PERT) are increasingly utilizing catheter-directed therapies, particularly mechanical thrombectomy, leading to significantly lower in-hospital mortality and shorte

Jan 2, 2026Sign in to read
Neurology

Endovascular Thrombectomy for Basilar Artery Occlusion: 3-Year Outcomes Confirm Durable Clinical Benefits

Long-term data from the ATTENTION trial reveal that endovascular thrombectomy significantly improves functional outcomes and survival at three years for patients with basilar artery occlusion, establishing it as a durable standard of care.

Jan 1, 2026
Neurology

Giving Thrombolysis Late — Before Transfer for Thrombectomy — May Improve Outcomes in AIS-LVO: Evidence from a 20-Center French Cohort

A multicenter retrospective cohort found that IV thrombolysis started beyond 4.5 hours and before interhospital transfer for EVT was associated with higher rates of spontaneous recanalization during transfer and better 3‑month functional ou

Dec 9, 2025
Neurology

Pretransfer IV Thrombolysis in Basilar Artery Occlusion: Improved Recanalization and 3‑Month Outcomes Without Clear Safety Signals

In transferred patients with basilar artery occlusion (BAO), IV thrombolysis before transfer was associated with higher rates of basilar recanalization and better 3‑month functional outcomes, with no significant increase in mortality or 24‑

Dec 6, 2025Sign in to read
Neurology

Giving IV Thrombolysis in the Late Window Before Transfer for Thrombectomy: Improved Recanalization and 3‑Month Outcomes in a Multicenter French Cohort

A multicenter retrospective cohort (OPEN-WINDOW) found that IV thrombolysis given beyond 4.5 hours before interhospital transfer for EVT was associated with higher rates of recanalization during transfer and better 3‑month functional outcom

Dec 6, 2025Sign in to read
Clinical Updates

Intravenous Antihypertensives Post-Endovascular Thrombectomy: Implications for Functional Recovery in Acute Ischemic Stroke

Intravenous antihypertensive use within 24 hours after successful EVT in acute ischemic stroke associates with poorer functional outcomes and higher mortality, underscoring the need for cautious blood pressure management strategies post-thr

Sep 19, 2025
Clinical Updates

Optimizing Head Positioning in Large Vessel Occlusion Stroke Before Thrombectomy: Evidence from a Randomized Clinical Trial

A recent randomized clinical trial demonstrates that 0° head-of-bed positioning prior to thrombectomy in patients with large vessel occlusion stroke preserves neurological stability and reduces mortality compared to the conventional 30° ele

Sep 11, 2025
Neurology

Thrombolysis Before Thrombectomy May Raise ICH Risk After Stroke: A Comprehensive Review of Recent Evidence

A meta-analysis of over 2000 stroke patients found that intravenous thrombolysis (IVT) before endovascular treatment (EVT) modestly increases intracranial hemorrhage (ICH) risk, especially in patients with elevated glucose and blood pressur

Aug 19, 2025
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