TGFBR2

Hypoxia-Induced BACH1 Elevation Drives Pulmonary Hypertension via Activation of TGFBR2/SMAD Signaling

BACH1 stabilization under hypoxia promotes pulmonary hypertension by enhancing TGFBR2/SMAD pathway activity in pulmonary artery smooth muscle cells, suggesting BACH1 as a promising therapeutic target for PH.