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Patient-Derived Neuronal Synapse Deficits Predict Brain Network Abnormalities and Cognitive Impairment in Schizophrenia
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Patient-Derived Neuronal Synapse Deficits Predict Brain Network Abnormalities and Cognitive Impairment in Schizophrenia

By MedXY|May 15, 2026

A multimodal translational study links genetically driven synaptic deficits in patient-derived neurons to cortical structure, electrophysiology, and cognition in schizophrenia, supporting biologically informed stratification of cognitive im

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