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Prophylactic Strategies to Prevent Infection in Lower Limb Peripheral Arterial Reconstruction: Evidence and Clinical Implications
Cardiologyperipheral arterial diseaseprophylactic antibiotics

Prophylactic Strategies to Prevent Infection in Lower Limb Peripheral Arterial Reconstruction: Evidence and Clinical Implications

By MedXY|Dec 17, 2025

Cochrane review shows prophylactic antibiotics may reduce SSI risk in peripheral arterial reconstruction; closed incision negative pressure therapy offers possible benefit but evidence is low.

Assessing the Value of Preoperative Antibiotics in Uncomplicated Acute Appendicitis: Insights from the PERFECT-Antibiotics Trial
Clinical Updatesacute appendicitisprophylactic antibiotics

Assessing the Value of Preoperative Antibiotics in Uncomplicated Acute Appendicitis: Insights from the PERFECT-Antibiotics Trial

By MedXY|Sep 28, 2025

Preoperative antibiotics in uncomplicated acute appendicitis do not reduce appendiceal perforation risk but lower surgical site infections. This large multicenter trial clarifies their limited role while awaiting timely appendectomy.

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