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Optimizing Smoking Cessation Interventions in Lung Cancer Screening: Insights from the CASTL Trial

By MedXY|Jul 11, 2026

The CASTL trial evaluated efficient combinations of tobacco cessation interventions for smokers undergoing lung cancer screening, identifying loss-framed messaging with nicotine replacement therapy as the most cost-effective strategy.

Embedding Tobacco Treatment Into Cancer Care Achieved Universal Screening but Exposed Persistent Gaps in Cessation Assistance

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Optimizing Smoking Cessation Interventions in Lung Cancer Screening: Insights from the CASTL Trial

Embedding Tobacco Treatment Into Cancer Care Achieved Universal Screening but Exposed Persistent Gaps in Cessation Assistance

Beyond the Initial Quit: Mobile Chat Messaging as a Scalable Solution for Smoking Relapse Prevention

Efficacy of mHealth Interventions for Smoking Cessation in Tuberculosis Patients: Insights from a Cluster Randomized Clinical Trial

Electronic Cigarettes for Smoking Cessation: An Updated Review

Nicotine E-Cigarettes Show Higher Quit Rates Than Traditional Nicotine Replacement Therapy

Stopping Smoking Is Associated With Better Recovery From Other Substance Use Disorders: Longitudinal Evidence From a US National Cohort

Quit Smoking Anytime: How Stopping in Midlife Can Preserve Your Memory and Thinking Skills

Mid-to-Late-Life Smoking Cessation Slows Long-Term Cognitive Decline: Insights from a 12-Country Longitudinal Study

Optimizing Nurse-Led Smoking Cessation: Insights from a Systematic Review and Network Meta-Analysis

Cytisinicline Enhances Smoking Cessation in COPD Patients: Post Hoc Insights from the ORCA-2 and ORCA-3 Trials

Smart-T Digital Intervention Enhances Smoking Cessation Among Low-Income Adults: Insights from a Randomized Clinical Trial

Optimizing Smoking Cessation in Major Depressive Disorder: Varenicline Outperforms Bupropion and Nicotine Patch with Comparable Safety

Cytisinicline’s Promise in Smoking Cessation: Insights from the ORCA Phase 3 Replication Trial

Esketamine in Lung Cancer Patients with Major Depression: Efficacy for Smoking Cessation and Treatment-Resistant Depression

E-cigarettes versus Combination Nicotine Replacement Therapy for Smoking Cessation in Substance Use Disorder Patients: Integrative Analysis of Recent Trials and Longitudinal Patterns