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Post-Transplant Cyclophosphamide as a Potent Strategy for Bronchiolitis Obliterans Syndrome Prevention: A Comprehensive Clinical Synthesis
Clinical UpdatesBOScGvHD

Post-Transplant Cyclophosphamide as a Potent Strategy for Bronchiolitis Obliterans Syndrome Prevention: A Comprehensive Clinical Synthesis

By MedXY|Mar 28, 2026

This review evaluates the role of post-transplant cyclophosphamide (PTCy) in reducing the risk of bronchiolitis obliterans syndrome (BOS), highlighting recent multicenter data that demonstrates a 75% risk reduction mediated by the preventio

Allogeneic HCT Rebounds, PTCy Reshapes Donor Choice, and CAR‑T Use Surges: Key Trends from the 2013–2023 CIBMTR Activity Report
Hematology-OncologyCAR‑TGVHD prophylaxis

Allogeneic HCT Rebounds, PTCy Reshapes Donor Choice, and CAR‑T Use Surges: Key Trends from the 2013–2023 CIBMTR Activity Report

By MedXY|Nov 12, 2025

CIBMTR’s 2013–2023 registry update shows a 2023 rebound in allogeneic HCT—driven by older adults—widespread adoption of post‑transplant cyclophosphamide (PTCy) across donor types, increasing mismatched donor use, and rapid expansion o

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