Hematology-Oncologymultiple myelomaproteasome inhibitor resistance
USP8 as a Therapeutic Target in B Cell Proteostasis and Multiple Myeloma Resistance
By MedXY|Aug 12, 2026
USP8 regulates proteostasis in B cells and multiple myeloma, influencing cellular survival and response to therapy. Targeting USP8 reveals new opportunities for overcoming proteasome inhibitor resistance in multiple myeloma.