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The TRICORDER trial demonstrates that while AI stethoscopes are capable of detecting heart failure, atrial fibrillation, and valvular disease, their real-world implementation in UK primary care did not yield a statistically significant incr
This article examines the CHIIP study, a randomized clinical trial evaluating whether survivorship care plan-based counseling improves cardiovascular risk factor control in childhood cancer survivors. Findings suggest that while documentati
A randomized clinical trial in Jamaica demonstrates that a hybrid model of in-person and remote parenting support delivered via primary care significantly improves child developmental outcomes and parenting behaviors, offering a scalable so
The BE IMMUNE randomized trial demonstrates that combining patient text reminders, clinician EHR pended orders, and peer comparisons increases flu vaccination by 5.1 percentage points among adults aged 50 and older, highlighting the efficac
The CLARO randomized clinical trial investigated whether a collaborative care model could improve outcomes for patients with opioid use disorder and co-occurring depression or PTSD. The study found no statistically significant advantages ov
A randomized trial of 402 US primary care physicians found that presenting two or more appropriate treatment alternatives (vs one) increased clinicians’ likelihood of changing from a status quo plan to an evidence‑based alternative, especia
A concise overview of the newly developed Core Outcome Set for healthy aging in primary care—12 prioritized outcomes to standardize evaluation of health-promotion interventions and improve comparability across studies and programs.
A multicenter randomized noninferiority trial found that GP observation after pediatric ventilation tube insertion produced audiometric outcomes at 2 years that were noninferior to routine ENT follow-up, with no increase in complications.
A pragmatic cluster randomized trial found that adding OUD-specific components to collaborative care in primary care clinics reduced days of opioid use more than collaborative care for mental health alone, without clear additional mental he
A pragmatic trial comparing SSRIs and written exposure therapy in primary care PTSD treatment found similar effectiveness initially; switching to SNRI was superior to WET augmentation for SSRI nonresponders.
Rising early-onset cancer incidence appears driven largely by increased diagnostic scrutiny and overdiagnosis rather than a true surge in disease, altering screening and management approaches in primary care.
A cluster randomized trial in veterans assessed peer coaching for weight management, showing improved program attendance but no significant 12-month weight loss difference versus enhanced usual care.
This trial assessed if videos and infographics from primary care physicians improve flu vaccination rates; overall effects were minimal, but notable improvements occurred in children.
A cluster randomized trial demonstrates that an electronic health record–integrated clinical decision support system increases naloxone prescriptions and opioid use disorder treatments in primary care but does not change diagnosis rates or
This study compares ChatGPT-4o and family physicians in answering 200 common primary care questions, revealing AI’s superior performance in appropriateness, accuracy, comprehensiveness, and empathy, highlighting its potential in enhancing p
A global meta-analysis reveals that over 40% of primary care prescriptions contain antibiotics, with more than half being inappropriate, highlighting urgent needs for improved antimicrobial stewardship worldwide.
AI decision support significantly improves primary care clinicians’ accuracy in spirometry diagnosis, especially for COPD, addressing a key gap in respiratory disease management.
