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Reduced Intestinal Epithelial GPX4 Expression Predicts Postoperative Crohn’s Disease Recurrence and Offers a Novel Therapeutic Target
GastroenterologyCrohn’s diseasegastroenterology

Reduced Intestinal Epithelial GPX4 Expression Predicts Postoperative Crohn’s Disease Recurrence and Offers a Novel Therapeutic Target

By MedXY|Mar 22, 2026

A breakthrough study identifies epithelial Glutathione peroxidase 4 (GPX4) deficiency as a potent predictor of Crohn’s disease recurrence after surgery. The research links this biomarker to endoplasmic reticulum stress and highlights

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