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Aspirin vs. Clopidogrel Monotherapy Following PCI: Insights from the STOPDAPT-3 1-Year Follow-up
CardiologyAntiplatelet TherapyAspirin

Aspirin vs. Clopidogrel Monotherapy Following PCI: Insights from the STOPDAPT-3 1-Year Follow-up

By MedXY|Oct 9, 2025

The STOPDAPT-3 trial compared aspirin and clopidogrel monotherapy after short dual antiplatelet therapy in PCI patients, showing similar cardiovascular and bleeding outcomes at 1 year.

Aspirin-Free Strategy in High Bleeding Risk PCI Patients: Insights from STOPDAPT-3 Subgroup Analysis
Cardiologyacute coronary syndromePCI

Aspirin-Free Strategy in High Bleeding Risk PCI Patients: Insights from STOPDAPT-3 Subgroup Analysis

By MedXY|Oct 9, 2025

In high bleeding risk patients undergoing PCI, aspirin-free prasugrel monotherapy fails to reduce major bleeding and shows increased myocardial infarction risk in ACS but not non-ACS patients, suggesting selective use post-PCI.

Intravascular Imaging-Guided PCI vs CABG for Left Main or 3-Vessel Disease: Bridging the Outcome Gap
CardiologyCABGIntravascular Imaging

Intravascular Imaging-Guided PCI vs CABG for Left Main or 3-Vessel Disease: Bridging the Outcome Gap

By MedXY|Oct 9, 2025

Recent study shows intravascular imaging-guided PCI may offer comparable 3-year outcomes to CABG in patients with left main or 3-vessel coronary disease, challenging prior assumptions favoring surgery.

Immediate Versus Staged Complete Revascularisation in STEMI with Multivessel Disease: Insights from the OPTION-STEMI Trial
CardiologyMultivessel DiseasePCI

Immediate Versus Staged Complete Revascularisation in STEMI with Multivessel Disease: Insights from the OPTION-STEMI Trial

By MedXY|Oct 8, 2025

The OPTION-STEMI trial evaluated the safety and efficacy of immediate versus staged complete revascularisation during index admission in STEMI patients with multivessel disease, finding no non-inferiority of immediate approach at 1 year.

Comparing Health Status Outcomes of PCI and CABG in Chronic Coronary Disease: Insights from ISCHEMIA
CardiologyCABGHealth Status

Comparing Health Status Outcomes of PCI and CABG in Chronic Coronary Disease: Insights from ISCHEMIA

By MedXY|Oct 6, 2025

The ISCHEMIA trial reveals that both PCI and CABG improve health status over conservative management in chronic coronary disease, with CABG offering superior angina relief at 1 year but similar benefits to PCI by 3 years.

Periprocedural Myocardial Injury after Elective PCI: Incidence and Impact on Long-Term Mortality
Cardiologylong-term mortalitymyocardial injury

Periprocedural Myocardial Injury after Elective PCI: Incidence and Impact on Long-Term Mortality

By MedXY|Oct 3, 2025

Post-PCI myocardial injury defined by elevated CKMB is common and linked to increased long-term mortality, with more complex coronary anatomy predicting the injury occurrence.

Decoding High‑Risk Enrollment in TWILIGHT: How Risk Feature Burden Shapes Ischemic and Bleeding Outcomes and the Consistent Benefit of Ticagrelor Monotherapy
Cardiologybleeding riskPCI

Decoding High‑Risk Enrollment in TWILIGHT: How Risk Feature Burden Shapes Ischemic and Bleeding Outcomes and the Consistent Benefit of Ticagrelor Monotherapy

By MedXY|Oct 2, 2025

Posthoc analysis of TWILIGHT shows that ischemic risk rises with the number of high‑risk features, bleeding does not, and ticagrelor monotherapy after 3 months reduces bleeding versus ticagrelor plus aspirin without increasing ischemic even

Percutaneous versus Surgical Approaches in Aortic Stenosis with Complex Coronary Disease: TCW Trial Insights
Cardiologyaortic stenosisCABG

Percutaneous versus Surgical Approaches in Aortic Stenosis with Complex Coronary Disease: TCW Trial Insights

By MedXY|Oct 1, 2025

The TCW trial demonstrates that FFR-guided PCI plus TAVI is non-inferior and even superior to SAVR plus CABG in elderly patients with severe aortic stenosis and complex coronary artery disease.

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