Our website uses essential cookies and, with your consent, additional cookies to measure performance and improve our services. Cookie Policy.
You can change your choice at any time.
Tag
Intravenous magnesium sulfate added to paracetamol increased early headache-treatment success in the emergency department, but the pain relief was modest and below usual clinical importance thresholds. It also reduced rescue analgesia needs
In the NEUROTHERM randomized pharmacodynamic trial, a single IV dose of paracetamol reduced intracerebral temperature by a mean 0.6°C in febrile brain‑injured patients and kept temperatures <38.5°C for a median 3.6 hours versus virtually
In a double‑blind RCT of 99 febrile brain‑injured patients with intracerebral thermal probes, a single IV dose of paracetamol reduced mean cerebral temperature by 0.6°C versus placebo and kept cerebral temperature <38.5°C for a median 3.
An umbrella review of systematic reviews finds low to critically low confidence in studies linking prenatal paracetamol exposure to autism or ADHD; sibling-controlled analyses largely attenuate associations. Clinical guidance: use lowest ef