P53

3 · 20 / page

Ask MedXY AI

Latest news

Tag

Hematology-Oncologybone marrow failureHematopoiesis

Unraveling MDM4 Haploinsufficiency: A Novel TP53-Dependent Mechanism Driving Bone Marrow Failure Syndromes

By MedXY|Jul 17, 2026

MDM4 haploinsufficiency activates p53, causing diverse bone marrow failure phenotypes and hypocellular MDS, highlighting the pivotal MDM4-p53 axis in hematopoietic regulation and potential targets for intervention.

Activity of PROTAC MDM2 Degrader in Primary Leukemia Cells and PDX Models

Hematology-OncologyAMLBệnh Bạch Cầu Tế Bào Phôi

P53

Latest news

Unraveling MDM4 Haploinsufficiency: A Novel TP53-Dependent Mechanism Driving Bone Marrow Failure Syndromes

Activity of PROTAC MDM2 Degrader in Primary Leukemia Cells and PDX Models

Curcumin Mitigates Methotrexate-Induced Ovarian Damage: Insights into Antioxidant Protection via PARP-1 and P53 Modulation