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Critical Careextubation failureHigh-flow nasal cannula

Evaluating High-Flow Nasal Cannula Oxygen Use During Noninvasive Ventilation Breaks After Extubation: Clinical Outcomes from a Multicenter Observational Study

By MedXY|Jul 17, 2026

This study examines whether high-flow nasal cannula oxygen during breaks from noninvasive ventilation post-extubation reduces extubation failure compared to standard oxygen therapy in high-risk patients.

Internal Medicinenoninvasive ventilationobesity hypoventilation syndrome

Effectiveness of Automatically-Adjusted vs Manually-Adjusted Noninvasive Ventilation in Obesity Hypoventilation Syndrome: A Randomized Clinical Trial

By MedXY|May 21, 2026

In ambulatory patients with obesity hypoventilation syndrome, automatically-adjusted noninvasive ventilation was as effective as manually adjusted NIV over 12 months and more cost-effective, offering a simpler path to treatment.

Critical Carecritical careextubation failure

Rescue Noninvasive Ventilation After Extubation: High Failure but No Clear Increase in Hospital Mortality — A Post‑hoc RINO Trial Analysis

By MedXY|Nov 6, 2025

A post‑hoc analysis of the RINO trial found rescue NIV for post‑extubation respiratory failure had a 58% failure rate but was associated with lower ICU mortality and no clear increase in hospital mortality when applied with prespecified re‑