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Maternal Nipocalimab Therapy for Severe HDFN: Evidence of Neonatal Safety and Immunological Recovery
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Maternal Nipocalimab Therapy for Severe HDFN: Evidence of Neonatal Safety and Immunological Recovery

By MedXY|Jan 31, 2026

The UNITY study demonstrates that antenatal nipocalimab treatment for severe HDFN effectively reduces fetal risk while resulting in only transient neonatal hypogammaglobulinemia. Findings confirm low fetal drug exposure and robust long-term

FcRn blockade with nipocalimab reduces disease activity in moderate‑to‑severe Sjögren’s syndrome: positive phase 2 DAHLIAS results
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FcRn blockade with nipocalimab reduces disease activity in moderate‑to‑severe Sjögren’s syndrome: positive phase 2 DAHLIAS results

By MedXY|Nov 27, 2025

In DAHLIAS, intravenous nipocalimab 15 mg/kg every 2 weeks for 22 weeks significantly reduced ClinESSDAI scores versus placebo in anti‑Ro seropositive patients with moderate‑to‑severe Sjögren’s disease, with a safety profile similar to plac

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