Hematology-OncologyAMLBệnh Bạch Cầu Tế Bào Phôi
Activity of PROTAC MDM2 Degrader in Primary Leukemia Cells and PDX Models
By MedXY|May 27, 2026
MD-265, a PROTAC MDM2 degrader, showed strong anti-leukemia activity in primary AML cells and mouse PDX models, outperformed a conventional MDM2 inhibitor, and spared normal stem cells relatively well.