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Prevalence and Clinical Characteristics of Macro-TSH in Patients with Subclinical Hypothyroidism
Diabetes & EndocrinologyLevothyroxinemacro-TSH

Prevalence and Clinical Characteristics of Macro-TSH in Patients with Subclinical Hypothyroidism

By MedXY|Jun 7, 2026

Macro-TSH was rare but clinically important in patients with subclinical hypothyroidism, sometimes mimicking true thyroid disease and leading to unnecessary levothyroxine use. Specialized testing confirmed multiple immunoglobulin-linked TSH

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