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Unraveling Mild-to-Moderate COPD: Distinct Phenotypes and Prognostic Diversity from a Community Cohort Study

This study reveals heterogeneous clinical phenotypes in mild-to-moderate COPD, demonstrating significant variability in exacerbation risk and lung function decline, emphasizing precision medicine for early intervention.

Nov 4, 2026
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Predicting Lung Function Decline in COPD via One-Year CT Emphysema Subtype Progression: Insights from SPIROMICS

SPIROMICS study demonstrates that progression of CT-detected emphysema subtypes over one year independently predicts accelerated FEV₁ decline, offering valuable intermediate endpoints for COPD clinical trials.

Sep 29, 2026Sign in to read
Clinical Updates

Mosaic Loss of Y Chromosome Links to Pulmonary Decline, Emphysema, and Accelerated Epigenetic Aging in Men: A Comprehensive Review

Mosaic loss of Y chromosome (mLOY) in men is strongly associated with diminished lung function, increased emphysema severity, and faster epigenetic aging, positioning mLOY as a novel biomarker for respiratory aging and COPD risk in males.

Jul 15, 2026

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