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Self-Reinforcing IL-1β Signaling Accelerates TCF3::HLF-Positive B-ALL Development and Relapse
Hematology-OncologyB-ALLbone lesions

Self-Reinforcing IL-1β Signaling Accelerates TCF3::HLF-Positive B-ALL Development and Relapse

By MedXY|May 27, 2026

Researchers found that IL-1β signaling drives growth, relapse, and bone damage in TCF3::HLF-positive B-ALL, suggesting IL-1β blockade may offer a new treatment strategy.

Predictive Value of Sex Chromosome Loss in Sex-Mismatched Stem Cell Transplantation
Hematology-Oncologybệnh huyết họcLeukemia Relapse

Predictive Value of Sex Chromosome Loss in Sex-Mismatched Stem Cell Transplantation

By MedXY|Mar 28, 2026

This study identifies late-onset sex chromosome loss as a critical biomarker for predicting relapse and survival outcomes in patients following sex-mismatched stem cell transplantation.

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