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The ReCCLAIM II trial demonstrates that rapid systemic hypothermia during mechanical thrombectomy for large-vessel occlusion stroke is feasible without delaying reperfusion, showing trends toward reduced infarct volume but raising safety co
An invasive, placebo‑controlled n‑of‑1 study shows that greater coronary collateral flow is associated with higher ischemic burden but lower pain intensity during controlled coronary occlusion, helping explain the weak correlation between s
The ISCHEMIA trial reveals that both PCI and CABG improve health status over conservative management in chronic coronary disease, with CABG offering superior angina relief at 1 year but similar benefits to PCI by 3 years.
This comprehensive review synthesizes evidence on Tongxinluo’s mechanisms and clinical benefits in myocardial infarction, acute coronary syndrome, and ischemia, highlighting patient subgroup analyses and current gaps in clinical evidence.
