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An invasive, placebo‑controlled n‑of‑1 study shows that greater coronary collateral flow is associated with higher ischemic burden but lower pain intensity during controlled coronary occlusion, helping explain the weak correlation between s
The ISCHEMIA trial reveals that both PCI and CABG improve health status over conservative management in chronic coronary disease, with CABG offering superior angina relief at 1 year but similar benefits to PCI by 3 years.
This comprehensive review synthesizes evidence on Tongxinluo’s mechanisms and clinical benefits in myocardial infarction, acute coronary syndrome, and ischemia, highlighting patient subgroup analyses and current gaps in clinical evidence.