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Integrin αIIbβ3 Deficiency Impairs Platelet Formation Through Serine Metabolic Dysregulation in Megakaryocytes
Hematology-OncologyGlanzmann thrombastheniaintegrin αIIbβ3

Integrin αIIbβ3 Deficiency Impairs Platelet Formation Through Serine Metabolic Dysregulation in Megakaryocytes

By MedXY|Sep 21, 2026

This study reveals that integrin αIIbβ3 deficiency in megakaryocytes disrupts serine metabolism, leading to reduced platelet production and shedding light on the complex pathophysiology underlying Glanzmann thrombasthenia.

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