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Impact of Mutated p53 on Type I Interferon Pathway Expression in Endometrial Cancer: Immune Modulatory Insights
newsI型インターフェロンimmune signaling

Impact of Mutated p53 on Type I Interferon Pathway Expression in Endometrial Cancer: Immune Modulatory Insights

By MedXY|Sep 12, 2026

This study reveals distinct alterations in the type I interferon pathway expression and signaling linked to mutated p53 subtypes in endometrial cancer, highlighting differing immune microenvironments that impact prognosis and therapeutic co

Molecular and Spatial Differences in the Tumor Microenvironment of High-Grade Serous Ovarian Cancer With Short vs Long-Term Survival
newsfibroblastshigh-grade serous ovarian cancer

Molecular and Spatial Differences in the Tumor Microenvironment of High-Grade Serous Ovarian Cancer With Short vs Long-Term Survival

By MedXY|May 26, 2026

This study found that advanced high-grade serous ovarian cancers from short-term survivors had more fibroblasts and stromal invasion signals, while tumors from long-term survivors showed stronger immune pathways, suggesting the tumor microe

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