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Gastroenterologydrug-induced liver injuryDILI

Navigating Drug-Induced Liver Injury in Clinical Trials: Insights and Updates from FDA Experts

By MedXY|Sep 7, 2026

Drug-Induced Liver Injury (DILI) remains a pivotal challenge in drug development, with evolving drug modalities and clinical trial designs prompting updated regulatory perspectives from FDA specialists.

GastroenterologyfezolinetantFAERS

Postmarketing Data Link Fezolinetant Primarily to Early Transaminase Elevations Rather Than Overt Liver Injury

By MedXY|Aug 18, 2026

FAERS postmarketing data suggest fezolinetant is associated with an early hepatic adverse event reporting signal, driven mainly by liver enzyme elevations rather than consistent severe clinical liver injury.