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Digitoxin Revisited: A Renewed Therapeutic Avenue for Advanced Heart Failure Patients

By MedXY|Oct 5, 2025

The DIGIT-HF trial reveals that adding low-dose digitoxin to standard heart failure treatment reduces hospitalization and all-cause mortality in symptomatic HFrEF patients, highlighting a potential resurgence for this historic cardiac glyco

Heart Failure Isn’t Scary — Ignoring Early Signs Is: Prevention for 6 High-Risk Groups

Cardiologyearly symptomsheart failure

heart failure

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Digitoxin Revisited: A Renewed Therapeutic Avenue for Advanced Heart Failure Patients

Heart Failure Isn’t Scary — Ignoring Early Signs Is: Prevention for 6 High-Risk Groups

Diuretic-Sparing Potential of Finerenone in Heart Failure with Mildly Reduced or Preserved Ejection Fraction: Insights from FINEARTS-HF

Unraveling Molecular Links Between Chronic Kidney Disease and Heart Failure via the Plasma Proteome

Left Atrial Volumetric/Mechanical Coupling Index in Heart Failure With Preserved Ejection Fraction

Risks and Realities of Withdrawing Heart Failure Medications After Ejection Fraction Improvement

Optimizing Blood Transfusion Strategies in Acute Myocardial Infarction with Anemia and Heart Failure: Insights from the MINT Trial

Decade-Long Insights into Deferred Versus Immediate Stenting in STEMI Patients: DANAMI-3-DEFER Trial Findings

Advancements in Transcatheter Edge-to-Edge Repair for Severe Tricuspid Regurgitation: Insights from the TRILUMINATE Pivotal Trial

Pregnancies Following Peri-Partum Cardiomyopathy: Insights from the ESC EuroObservational Research Programme

Leveraging AI-Driven Care to Significantly Reduce Heart Failure Readmissions: The Linea Model

Anaemia as a Predictor of Iron Dysregulation and Modulator of Empagliflozin Response in Heart Failure with Reduced Ejection Fraction: Insights from the EMPATROPISM-FE Trial

Impact of Structural Cardiac Abnormalities on the Efficacy and Safety of Sacubitril/Valsartan in Patients with Mildly Reduced or Preserved Ejection Fraction and Worsening Heart Failure: Insights from the PARAGLIDE-HF Trial

Enhancing Muscle Microvascular Function in Heart Failure: The Role of Acute BH4 Administration

Examining the Link Between Obesity and Kidney Outcomes in Heart Failure with Preserved Ejection Fraction

Evaluating Erythrocytosis Incidence and Thromboembolic Risk in HFrEF Patients Treated with SGLT2 Inhibitors

Dapagliflozin and Spironolactone: A Promising Combination for Heart Failure with Preserved Ejection Fraction

Evaluating the Heart Failure Risk in Type 2 Diabetes: Insights from 1.6 Million People in England

Heart Failure Risk with Pregabalin vs Gabapentin: New Evidence for Chronic Pain Management in Older Adults