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MedXY AI/MedXY News/Tag: heart failure with reduced ejection fraction
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Impact of Digitalis Glycosides on Cardiovascular Outcomes in HFmrEF and HFrEF: A Comprehensive Evidence Synthesis
Cardiologydigitalis glycosidesheart failure with mid-range ejection fraction

Impact of Digitalis Glycosides on Cardiovascular Outcomes in HFmrEF and HFrEF: A Comprehensive Evidence Synthesis

By MedXY|Sep 17, 2026

Digitalis glycosides reduce cardiovascular death or worsening heart failure events in HFmrEF and HFrEF patients over a median of 36–37 months, supported by randomized trials and meta-analyses highlighting their role in select heart failure

Vagal Nerve Stimulation in HFrEF Was Safe but Did Not Improve the Primary Composite Outcome in the ANTHEM-HFrEF Trial
CardiologyANTHEM-HFrEF
autonomic modulation

Vagal Nerve Stimulation in HFrEF Was Safe but Did Not Improve the Primary Composite Outcome in the ANTHEM-HFrEF Trial

By MedXY|May 23, 2026

In ANTHEM-HFrEF, vagal nerve stimulation in symptomatic HFrEF was feasible and safe, but the underpowered trial did not meet its primary efficacy endpoint after premature sponsor-driven termination.

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