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Evaluating Sphenopalatine Ganglion Block Dosage for Headache Relief in the Emergency Department
Emergency Medicinesphenopalatine ganglion blockbupivacaine

Evaluating Sphenopalatine Ganglion Block Dosage for Headache Relief in the Emergency Department

By MedXY|Sep 24, 2026

This randomized trial found that larger doses of bupivacaine for sphenopalatine ganglion block did not improve sustained headache relief in emergency patients compared to smaller doses, with good tolerability across all doses.

Atogepant Shows Better Tolerability and Efficacy Than Topiramate in Migraine Prevention: TEMPLE Trial Results
NeurologyMigrainereflectance confocal microscopy

Atogepant Shows Better Tolerability and Efficacy Than Topiramate in Migraine Prevention: TEMPLE Trial Results

By MedXY|Jul 25, 2026

The phase 3b TEMPLE trial found that atogepant 60 mg once daily led to fewer discontinuations due to adverse events and better migraine reduction than topiramate over 24 weeks.

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