GPVI

Loss of the Fibrinogen αC Region, Rather Than Hypofibrinogenemia Alone, Attenuates Experimental Arterial Thrombosis

Mouse and human observational data suggest that the fibrinogen αC region is a key determinant of arterial thrombosis under hypofibrinogenemic conditions, likely through platelet GPVI-dependent mechanisms.

Reticulated Platelets Drive Prothrombotic Signalling in Coronary Artery Disease — GPVI and PI3K Identified as Actionable Targets