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germline testing

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OB/GYN & Women's Health

Expanding the Genetic Landscape in Ovarian Carcinoma: Insights from the PERSONA-Ovary Trial on Germline and Somatic Testing

The PERSONA-Ovary trial demonstrates the feasibility and clinical value of unselected germline multigene panel testing alongside somatic BRCA analysis in ovarian carcinoma, revealing a 29.7% pathogenic variant prevalence and optimal testing

Oct 17, 2026Sign in to read
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Family History Misses Actionable Germline Variants in Many Ovarian Cancer Patients Over 70

A large real-world registry study shows that ovarian cancer patients aged 70 and older still carry clinically actionable germline variants, often without a reported family history, supporting broader age-inclusive genetic testing.

May 13, 2026Sign in to read

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