
Diabetes & EndocrinologyendocrinologyGCK-MODY
Impact of Polygenic Risk Scores on the Clinical Presentation and Glycaemic Variability of GCK-MODY
By MedXY|Mar 20, 2026
This article explores how polygenic background modifies GCK-MODY clinical phenotypes, influencing HbA1c levels and diagnostic thresholds. Findings highlight the distinct polygenic patterns in GCK-MODY compared to HNF1A-MODY, emphasizing the