Galectin-3

Galectin-3 Regulates Smooth Muscle Contraction and Blood Pressure by Modulating CaV1.2 Channel Function

Researchers found that Galectin-3 boosts CaV1.2 calcium channel activity in blood vessel muscle, increasing contraction and blood pressure. Blocking this interaction lowered blood pressure in animal models, suggesting a new target for hyper

Targeted Galectin-3 Inhibition for Portal Hypertension: Insights from the NAVIGATE Trial and Belapectin’s Role in MASH Cirrhosis