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The RETREAT-FRAIL trial found no survival benefit from progressively reducing antihypertensive medications in frail nursing home residents aged ≥80 with controlled blood pressure, supporting individualized treatment strategies.
A 12-week anti-inflammatory dietary education significantly improved frailty, nutritional status, inflammatory biomarkers, and quality of life in frail colorectal cancer patients undergoing chemotherapy.
Switching frail, elderly atrial fibrillation patients from warfarin to standard-dose DOAC reduced stroke, fatal and intracranial bleeding, and death, though gastrointestinal bleeding increased. Major bleeding and net clinical outcome remain
This 10-year study from England details delirium’s prevalence, associated factors like dementia and frailty, and its lasting impact on mortality and care needs in acute general medicine patients, supporting targeted screening and inte
Frailty in older hospitalized adults is strongly linked to discharge to post-acute care, increased 90-day readmission rates, and higher mortality, highlighting the need for targeted discharge planning using automated frailty assessments.