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Pubertal Delay Associated with Paternally Derived 15q11.2-q13 Duplication Syndrome and MKRN3 Overexpression: A Case Series
Diabetes & Endocrinologycase reportEndocrine dysfunction

Pubertal Delay Associated with Paternally Derived 15q11.2-q13 Duplication Syndrome and MKRN3 Overexpression: A Case Series

By MedXY|Sep 27, 2026

This report discusses four patients with paternally inherited 15q11.2-q13 duplications linked to MKRN3 overexpression, presenting with delayed puberty and varying degrees of hypogonadism.

Beyond the Lesion: Long-Term Cardiovascular, Neurologic, Psychiatric, and Endocrine Risks After Traumatic Spinal Cord Injury
Cardiologycardiovascular riskEndocrine dysfunction

Beyond the Lesion: Long-Term Cardiovascular, Neurologic, Psychiatric, and Endocrine Risks After Traumatic Spinal Cord Injury

By MedXY|Dec 15, 2025

A large retrospective cohort study shows traumatic spinal cord injury (TSCI) is associated with increased long-term cardiovascular, neurologic, psychiatric, and endocrine morbidity and higher mortality, even in previously healthy adults.

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