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Elafibranor

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Gastroenterology

Elafibranor as an Effective Second-Line Treatment to Normalize Alkaline Phosphatase in Primary Biliary Cholangitis with Incomplete Response to Ursodeoxycholic Acid: Synthesizing Evidence from the Phase III ELSPIRE Trial and Related Studies

Elafibranor demonstrates significant efficacy and safety in normalizing alkaline phosphatase among PBC patients inadequately responding to UDCA, establishing ALP normalization as a treatment goal and supporting its role as a second-line the

Nov 13, 2026
Gastroenterology

Elafibranor Shows Promise as a Safe and Effective Therapy for Primary Sclerosing Cholangitis: Insights from the Phase II ELMWOOD Trial

The phase II ELMWOOD trial demonstrates that elafibranor, a dual PPAR-α/δ agonist, is well tolerated and significantly improves biochemical markers in patients with primary sclerosing cholangitis over 12 weeks, warranting further investigat

Oct 29, 2025Sign in to read

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