Early-Onset Alzheimer Disease

MRI-Derived EOAD-Signature Atrophy as a Prognostic Biomarker in Early-Onset Mild Cognitive Impairment

Baseline cortical atrophy within an EOAD-specific brain signature predicts progression from mild cognitive impairment to dementia, providing a valuable MRI biomarker for individualized prognosis in early-onset Alzheimer disease.