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Corticostriatal Connectivity Reorganizes Before and After Motor Decline in Parkinson Disease
Neurologycorticostriatal connectivitynigrostriatal degeneration

Corticostriatal Connectivity Reorganizes Before and After Motor Decline in Parkinson Disease

By MedXY|Apr 19, 2026

Resting-state MRI and PET data suggest that corticostriatal networks remodel across nigrostriatal degeneration in Parkinson disease, with posterior caudate hyperconnectivity preceding major motor decline and posterior putaminal disconnectio

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