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Sex-Specific Risk Thresholds in Coronary Artery Disease: Why Plaque Burden Metrics Demand Re-evaluation in Women
Cardiologycoronary artery diseaseCoronary CTA

Sex-Specific Risk Thresholds in Coronary Artery Disease: Why Plaque Burden Metrics Demand Re-evaluation in Women

By MedXY|Mar 2, 2026

A secondary analysis of the PROMISE trial reveals that women face elevated cardiovascular risk at significantly lower coronary plaque thresholds than men, necessitating a paradigm shift toward sex-stratified interpretation of coronary CT an

Elevated Blood Pressure in Adolescence Predicts Dose‑Dependent Coronary Atherosclerosis in Middle Age: Implications for Early Detection and Prevention
CardiologyatherosclerosisCoronary CTA

Elevated Blood Pressure in Adolescence Predicts Dose‑Dependent Coronary Atherosclerosis in Middle Age: Implications for Early Detection and Prevention

By MedXY|Dec 2, 2025

A Swedish cohort study of 10,222 men linked adolescent blood pressure to coronary atherosclerosis by CCTA ~40 years later; higher systolic BP in adolescence, even in the ‘elevated’ range, was associated with greater odds of severe (>50%)

Long-Term Survival Outcomes After Initial Stress Testing Versus Coronary CTA in Suspected CAD: Insights from the PROMISE Trial
Cardiologycoronary artery diseaseCoronary CTA

Long-Term Survival Outcomes After Initial Stress Testing Versus Coronary CTA in Suspected CAD: Insights from the PROMISE Trial

By MedXY|Oct 9, 2025

The PROMISE trial’s 10-year follow-up shows no difference in all-cause or cardiovascular mortality between initial functional stress testing and anatomic coronary CTA in symptomatic patients with suspected coronary artery disease.

Enhancing Cardiovascular Risk Prediction and Outcomes with Coronary CT Angiography: Insights from the PROMISE and SCOT-HEART Trials
CardiologyCoronary CTAmyocardial infarction

Enhancing Cardiovascular Risk Prediction and Outcomes with Coronary CT Angiography: Insights from the PROMISE and SCOT-HEART Trials

By MedXY|Oct 3, 2025

Coronary CTA, guided by clinical risk models and advanced radiomic plaque analysis, improves prediction and prevention of myocardial infarction in patients with new-onset chest pain, particularly in those with low clinical likelihood of cor

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