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Should Some Colon Cancers Be Treated Before Surgery? What a New Trial Means for Patients

By MedXY|May 18, 2026

A major randomized trial found that chemotherapy before surgery did not improve 3-year disease-free survival in locally advanced colon cancer, but it still revealed important clues for more personalized treatment.

Closing the Gap: How Equitably Applying Minimally Invasive Surgery Could Transform Colon Cancer Outcomes

General Surgerycolon cancerhealth equity

colon cancer

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Should Some Colon Cancers Be Treated Before Surgery? What a New Trial Means for Patients

Closing the Gap: How Equitably Applying Minimally Invasive Surgery Could Transform Colon Cancer Outcomes

Postoperative ctDNA Identifies Stage III Colon Cancer Patients Who May Benefit from Adjuvant Celecoxib

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ctDNA-Guided Adjuvant Therapy in Stage III Colon Cancer: Prognostic Validation but No Benefit from Chemotherapy Intensification — Key Findings from the DYNAMIC-III Randomized Phase 2/3 Trial

Defining Cure in Stage II-III Colon Cancer: Insights from a Pooled Analysis of 15 Randomized Trials

Adjuvant Aspirin in PIK3CA-Mutated Colon Cancer: Insights from the SAKK 41/13 Randomized Trial

Structured Exercise after Adjuvant Chemotherapy for Colon Cancer: Impact on Survival Outcomes

Personalizing Oxaliplatin Dosing: Reducing Neurotoxicity in Stage III Colon Cancer—Insights from the LEANOX Trial