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This article examines the clinical and psychosocial factors influencing BRCA previvors’ decisions on timing delayed oophorectomy after risk-reducing salpingectomy, highlighting the nuanced balance between cancer anxiety and menopausal
A large real-world registry study shows that ovarian cancer patients aged 70 and older still carry clinically actionable germline variants, often without a reported family history, supporting broader age-inclusive genetic testing.
Final MAGNITUDE results show niraparib combined with abiraterone–prednisone improves radiographic PFS, time to symptomatic progression and delays cytotoxic chemotherapy in HRR‑altered mCRPC (notably BRCA1/2), preserves patient‑reported qual
This article discusses the application of the estimand framework to evaluate clinical effectiveness of risk-reducing early salpingectomy with delayed oophorectomy in women with high ovarian cancer risk due to BRCA mutations, based on data f
