
newsalveolar regenerationAT2-to-AT1 transdifferentiation
Unlocking Lung Repair: Prostaglandin I2 Receptor Activation Drives Alveolar Regeneration via JUN/p53 Pathway
By MedXY|Jul 13, 2026
Activation of the prostaglandin I2 receptor (IP) enhances alveolar epithelial regeneration by promoting AT2-to-AT1 cell transdifferentiation through modulation of the JUN/p53 signaling axis, offering a promising therapeutic avenue for lung