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A post hoc analysis of the BRIDGE-TNK trial reveals that intravenous tenecteplase before endovascular thrombectomy significantly improves functional independence in acute large-vessel occlusion stroke patients with extensive baseline ischem

NeurologyASPECTS

Endovascular Thrombectomy

Redefining Patient Selection for Endovascular Thrombectomy in Large-Core Ischemic Stroke: The Role of Quantitative Volumetry Beyond ASPECTS

By MedXY|Jul 8, 2026

This study identifies a volumetric threshold of 110 mL infarct size beyond which the benefit of thrombectomy diminishes, advocating volumetric assessment over ASPECTS scoring to optimize treatment selection and outcomes in large-core stroke

NeurologyASPECTSEndovascular Thrombectomy

Beyond ASPECTS: Defining the Therapeutic Limit of Endovascular Thrombectomy in Large-Core Ischemic Stroke

By MedXY|Jul 8, 2026

Recent evidence identifies volumetric thresholds surpassing ASPECTS scoring for optimizing thrombectomy candidacy in large-core ischemic stroke, highlighting a therapeutic ceiling at infarct volumes ≥110 mL.

NeurologyASPECTSNeuroimaging

Time-Dependent Topography: How Specific ASPECTS Regions Predict Outcomes in Early vs. Extended Window Large Vessel Occlusion Stroke

By MedXY|Feb 4, 2026

A post-hoc analysis of 1,040 LVO stroke patients reveals that the prognostic value of specific brain regions varies significantly between early (0-6h) and extended (6-24h) time windows, identifying the insula, caudate, and M6 as early-windo

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