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High Empathy, Low Accuracy: Can Generative AI Safely Navigate Alcohol Misuse Support?
AIAlcohol Misuseartificial intelligence

High Empathy, Low Accuracy: Can Generative AI Safely Navigate Alcohol Misuse Support?

By MedXY|Feb 2, 2026

A longitudinal study published in NEJM AI evaluates seven generative AI chatbots for alcohol misuse support, finding that while they excel in empathy and non-judgmental language, they frequently provide low-quality or inaccurate medical inf

AI-ECG Models for Heart Failure Screening Show High Accuracy in First-of-its-Kind Independent Comparison Study
AIartificial intelligenceCardiology

AI-ECG Models for Heart Failure Screening Show High Accuracy in First-of-its-Kind Independent Comparison Study

By MedXY|Jan 26, 2026

This independent validation study confirms that AI-enhanced ECG models effectively detect left ventricular systolic dysfunction across diverse populations, achieving AUROCs up to 0.93. However, significant barriers remain regarding model tr

AI-Driven Decision Support for Antibiotic Switching: Why Clinicians Value Caution Over Speed
AIantimicrobial stewardshipartificial intelligence

AI-Driven Decision Support for Antibiotic Switching: Why Clinicians Value Caution Over Speed

By MedXY|Jan 15, 2026

A randomized multimethod study reveals that while AI clinical decision support systems for antibiotic switching are well-received, their primary influence is reinforcing conservative prescribing. The study underscores that usability and cli

Multimodal AI Outperforms Clinical Nomograms in Predicting Metastasis for Post-Prostatectomy Biochemical Recurrence
AIartificial intelligenceprostate cancer

Multimodal AI Outperforms Clinical Nomograms in Predicting Metastasis for Post-Prostatectomy Biochemical Recurrence

By MedXY|Jan 10, 2026

A validated multimodal AI model using digital pathology and clinical data significantly improves risk stratification for prostate cancer patients with biochemical recurrence, identifying those who derive the greatest benefit from salvage ho

AI-Derived Sarcopenia Metrics Predict Survival Benefit from Anti-EGFR Therapy in RAS Wild-Type Metastatic Colorectal Cancer
AIartificial intelligencemetastatic colorectal cancer

AI-Derived Sarcopenia Metrics Predict Survival Benefit from Anti-EGFR Therapy in RAS Wild-Type Metastatic Colorectal Cancer

By MedXY|Jan 8, 2026

A deep learning analysis of the PanaMa trial reveals that the benefit of adding panitumumab to maintenance therapy for RAS wild-type mCRC is significantly higher in patients with a high muscle-bone ratio, suggesting a new AI-driven approach

AI-Based OCT Analysis Outperforms Human Experts in Predicting Outcomes from Non-Culprit Lesions: Insights from the PECTUS-AI Study
AIartificial intelligencecardiovascular outcomes

AI-Based OCT Analysis Outperforms Human Experts in Predicting Outcomes from Non-Culprit Lesions: Insights from the PECTUS-AI Study

By MedXY|Jan 3, 2026

The PECTUS-AI study demonstrates that AI-based identification of thin-cap fibroatheromas using OCT provides superior prognostic value for cardiovascular events compared to manual analysis, particularly when assessing the entire imaged coron

Dynamic Phenotyping in ARDS: AI-Driven Insights Reveal Why Corticosteroid Benefits Depend on Inflammatory State
Critical CareARDSartificial intelligence

Dynamic Phenotyping in ARDS: AI-Driven Insights Reveal Why Corticosteroid Benefits Depend on Inflammatory State

By MedXY|Dec 27, 2025

A groundbreaking study utilizing an AI classifier demonstrates that ARDS inflammatory phenotypes are dynamic and dictate corticosteroid efficacy. While hyperinflammatory patients benefit from steroids, hypoinflammatory patients face increas

AI-Detected Coronary Calcium Significantly Predicts Cardiovascular Risk in Patients with Immune-Mediated Inflammatory Diseases
AIartificial intelligencecardiovascular risk

AI-Detected Coronary Calcium Significantly Predicts Cardiovascular Risk in Patients with Immune-Mediated Inflammatory Diseases

By MedXY|Dec 25, 2025

AI-driven analysis of routine chest CTs reveals that coronary artery calcium is highly prevalent and strongly predictive of MACE and mortality in patients with IMIDs, identifying a critical treatment gap in this high-risk population.

AIartificial intelligenceEndovascular Thrombectomy

AI-Driven Imaging Decision Support Doubles Thrombectomy Rates in Real-World Stroke Care

By MedXY|Dec 19, 2025

A large-scale prospective study across England’s NHS reveals that AI imaging software significantly boosts endovascular thrombectomy rates for acute stroke patients. Implementation was associated with a 100% relative increase in treat

Artificial Intelligence-Enabled Prediction of Heart Failure Risk From Single-Lead Electrocardiograms: A Multinational Cohort Review
AIartificial intelligenceECG

Artificial Intelligence-Enabled Prediction of Heart Failure Risk From Single-Lead Electrocardiograms: A Multinational Cohort Review

By MedXY|Dec 5, 2025

This review evaluates AI algorithms predicting heart failure risk from noisy single-lead ECGs, synthesizing evidence from large multinational cohorts, highlighting improved risk stratification with AI-ECG models beyond traditional clinical

Neural Networks Predict Survival for Older Adults With Head and Neck Cancer — Useful, but Not Yet Practice-Changing
newsartificial intelligencegeriatric oncology

Neural Networks Predict Survival for Older Adults With Head and Neck Cancer — Useful, but Not Yet Practice-Changing

By MedXY|Nov 18, 2025

An international cohort study developed and externally validated artificial neural networks that stratify older adults with locoregionally advanced head and neck squamous cell carcinoma (HNSCC) treated with definitive chemoradiation. Models

AI-Augmented Screening Triples Detection Yield of Transthyretin Cardiac Amyloidosis in a Multisite Real-World Trial
AIartificial intelligenceATTR-CM

AI-Augmented Screening Triples Detection Yield of Transthyretin Cardiac Amyloidosis in a Multisite Real-World Trial

By MedXY|Nov 18, 2025

An AI-driven screening program (ATTRACTnet) applied to ECG, echocardiography, demographics and orthopedic history substantially increased case detection of transthyretin cardiac amyloidosis (ATTR‑CM) and led to rapid treatment initiation in

Does AI Make Endoscopists Lazy? New Multicentre Data Show Reduced Adenoma Detection After AI Exposure
AIAdenoma Detection Rateartificial intelligence

Does AI Make Endoscopists Lazy? New Multicentre Data Show Reduced Adenoma Detection After AI Exposure

By MedXY|Nov 9, 2025

A multicentre observational study reports a 6% absolute fall in adenoma detection rate for non‑AI colonoscopies after clinicians were exposed to AI-assisted polyp detection—raising concerns about endoscopist deskilling and the need for safe

How Eli Lilly and NVIDIA’s AI Supercomputer is Revolutionizing Drug Discovery
AIartificial intelligenceEli Lilly

How Eli Lilly and NVIDIA’s AI Supercomputer is Revolutionizing Drug Discovery

By MedXY|Nov 4, 2025

Eli Lilly and NVIDIA have partnered to launch the largest AI-powered supercomputing platform in pharma, aiming to accelerate drug discovery, personalize medicine, and enhance manufacturing through unprecedented computational power.

Evaluating AI-Led vs Human-Led Lifestyle Interventions in Prediabetes: Evidence from a Randomized Clinical Trial of the Diabetes Prevention Program
AIartificial intelligencediabetes

Evaluating AI-Led vs Human-Led Lifestyle Interventions in Prediabetes: Evidence from a Randomized Clinical Trial of the Diabetes Prevention Program

By MedXY|Oct 29, 2025

This review examines the first phase 3 randomized trial demonstrating that an AI-powered Diabetes Prevention Program lifestyle intervention is noninferior to human coaching in improving weight loss, HbA1c, and physical activity among adults

Artificial Intelligence in Imaging-Based Extranodal Extension Detection: Advancing Prognostication in HPV-Positive Oropharyngeal Cancer
AIartificial intelligenceExtranodal Extension

Artificial Intelligence in Imaging-Based Extranodal Extension Detection: Advancing Prognostication in HPV-Positive Oropharyngeal Cancer

By MedXY|Oct 22, 2025

An AI-driven model accurately detects imaging-based extranodal extension in HPV-positive oropharyngeal cancer from CT scans, improving outcome prediction beyond expert radiologist assessments and identifying patients at higher risk of poore

Enhancing Melanoma Prognosis: AI-Driven Quantification of Tumor-Infiltrating Lymphocytes Outperforms Traditional Pathology
AIartificial intelligencemelanoma

Enhancing Melanoma Prognosis: AI-Driven Quantification of Tumor-Infiltrating Lymphocytes Outperforms Traditional Pathology

By MedXY|Oct 21, 2025

This study demonstrates that an AI algorithm provides more reproducible and prognostically relevant assessment of tumor-infiltrating lymphocytes in melanoma compared to traditional pathologist methods, offering a promising tool to improve c

Artificial Intelligence-Detected Tumor-Infiltrating Lymphocytes as a Biomarker in Anti-PD-1-Based Therapy for Advanced Melanoma: Clinical Evidence and Translational Perspectives
AIartificial intelligenceimmune checkpoint inhibitors

Artificial Intelligence-Detected Tumor-Infiltrating Lymphocytes as a Biomarker in Anti-PD-1-Based Therapy for Advanced Melanoma: Clinical Evidence and Translational Perspectives

By MedXY|Oct 21, 2025

AI-detected tumor-infiltrating lymphocytes on routine histology independently predict response and survival in advanced melanoma treated with anti-PD-1 therapies, outperforming manual scoring and offering an accessible biomarker for immune

Navigating the AI Revolution in Health Care: Insights from the JAMA Summit
AIartificial intelligenceEquity

Navigating the AI Revolution in Health Care: Insights from the JAMA Summit

By MedXY|Oct 14, 2025

Artificial intelligence is reshaping health care, offering vast potential benefits alongside significant challenges. The JAMA Summit emphasizes the need for robust evaluation, equitable deployment, and multi-stakeholder collaboration to ens

Harnessing Artificial Intelligence for Diagnosing Sexually Transmitted Infections and Anogenital Dermatoses: Insights from a Systematic Review and Meta-Analysis
AIartificial intelligenceSexually Transmitted Infections

Harnessing Artificial Intelligence for Diagnosing Sexually Transmitted Infections and Anogenital Dermatoses: Insights from a Systematic Review and Meta-Analysis

By MedXY|Oct 6, 2025

AI demonstrates high accuracy in identifying mpox and other anogenital conditions from clinical images, yet significant research gaps and validation needs remain before clinical adoption.

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