APOEε4

Sex, Race, and Ancestry Converge to Shape Amyloid Pathology: Evidence from a Large-Scale Admixed Autopsy Study

This cross-sectional study of 2,268 autopsies reveals that female sex, APOEε4 status, and African ancestry independently and jointly influence neuritic plaque burden, suggesting that current Alzheimer’s biomarker thresholds may need refinem

Oral Valiltramiprosate in APOEε4/ε4 Carriers with Early Alzheimer’s Disease: Insights from the Phase III APOLLOE4 Trial