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Decoding Dementia in Lewy Body Disease: The Interplay of Quantitative Pathology, APOE Genotype, and Disease Heterogeneity
By MedXY|Apr 2, 2026
Recent advances in digital pathology and machine learning reveal that APOE ε4 promotes proteinopathy and modifies dementia thresholds, while multi-modal trajectories suggest distinct pathways for disease progression in Lewy body disease.