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α-Gal Sensitization as a Cause of Severe Allergic Reactions in Group O Recipients of Group B/AB Plasma and Platelets
Allergy & ImmunologyABO incompatibilityallergic transfusion reactions

α-Gal Sensitization as a Cause of Severe Allergic Reactions in Group O Recipients of Group B/AB Plasma and Platelets

By MedXY|Jun 25, 2026

Severe allergic transfusion reactions in group O recipients receiving group B or AB plasma or platelets are linked to IgE antibodies against the α-Gal epitope, highlighting a novel immunological mechanism and potential risk stratification a

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