Alcohol-Associated Hepatitis

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Integrating Therapies for Alcohol Use Disorder in Alcohol-Associated Hepatitis Clinical Trials: Advancing Composite Endpoints for Improved Outcomes

Alcohol-associated hepatitis (AH) carries high morbidity and mortality, with no approved therapies addressing both liver injury and alcohol misuse. This article explores integrated trial designs using composite endpoints combining liver and

Oct 28, 2026

Gastroenterology

Metabolic Dysfunction Did Not Worsen Short-Term Survival in Severe Alcohol-Associated Hepatitis in a Global Prospective Cohort

In a 32-center international cohort, cardiometabolic risk factors were common in alcohol-associated hepatitis but did not independently increase 180-day mortality after adjustment for liver disease severity and competing transplant risk.

May 26, 2026

Clinical Updates

Temporal Dynamics of the Circulating Cytokinome in Severe Alcohol-Associated Hepatitis: A Longitudinal Clinical Analysis

This review analyzes the longitudinal kinetics of 43 inflammatory biomarkers in patients with severe alcohol-associated hepatitis, comparing IL-1 receptor antagonism and corticosteroid therapy, highlighting treatment-specific signatures and

Mar 23, 2026Sign in to read